I have been working on the design and development of ad-hoc methods for curvilinear structures segmentation.
This work was motivated by the fact that state-of-the-art approaches tend to fail when dealing with corneal nerve fibres captured via confocal microscopy. Qualitative and quantitative results show that our methods outperform previously reported methods on several dataset.
Automated curvilinear structure detection in images capturing corneal nerve fibres and neuronal trees with various technical challenges such as confounding non-target structures, low contrast, low resolution, non-uniform illumination, high tortuosity level and fragmentation.