During this reporting period, the mathematical model of the retinal vascular network was improved, and some results for paper were obtained. Work on manuscript, dedicated to mathematical model was started. In addition to modeling part of my work, animal experiments on rats eyes were carried out. Now, these experiments are focused on detection of retinal reaction on flickering-light stimulus. Furthermore, I am involved in experiments on eggs chorioallantoic membrane, which are focused on vascular network remodelling. To get the rat retinal images and images of eggs chorioallantoic membrane we using Laser Speckle Contrast method, that is “full-field” and non invasive technique.