The fully automated framework for curvilinear structure tortuosity quantification has been completed and tested extensively. It consists of the combination of a new ridge detector designed and developed for detecting tortuous structures (SCIRD) and learned context filters. Qualitative (the image attached shows a comparison of our curvilinear structur detector, SCIRD and state-of-the-art methods) and quantitative results show that our system compare favourably with previously reported methods and achieve a level of accuracy comparable or better than three experience observers. The original building blocks of the proposed framework have been accepted as three MICCAI conference papers and a journal paper presenting the system will be submitted soon. Please refer to my webpage for further details.