Weiwei Xiang – Progress Report 6

The final results of my project show that after occlusion, unidirectional flow towards the occlusion site was established. Diameters exhibited an immediate decrease, an ensuing increase with a time constant of 2.53 ± 0.77h (mean ± SD, n = 13 CAMs) and then a plateau of up to 60% above baseline without significant vascular tone change. WSS exhibited an immediate increase, a linear decrease to baseline approximately 12h post-occlusion and then remained unchanged. WSS increase upon occlusion and sustained diameter changes were correlated. WSS change only partly mirrored the diameter change rate through 24h post-occlusion.

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